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human tissue expression patterns  (Human Protein Atlas)

 
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    Human Protein Atlas human tissue expression patterns
    Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA <t>expression</t> profiles of proteins in the synaptic bouton complex across different tissues sampled by the <t>Human</t> Protein Atlas. This shows the complex is highly specific for cerebral cortex <t>tissue.</t> No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.
    Human Tissue Expression Patterns, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human tissue expression patterns/product/Human Protein Atlas
    Average 90 stars, based on 1 article reviews
    human tissue expression patterns - by Bioz Stars, 2026-02
    90/100 stars

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    1) Product Images from "Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes"

    Article Title: Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

    Journal: Molecular Systems Biology

    doi: 10.15252/msb.20167490

    Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA expression profiles of proteins in the synaptic bouton complex across different tissues sampled by the Human Protein Atlas. This shows the complex is highly specific for cerebral cortex tissue. No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.
    Figure Legend Snippet: Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA expression profiles of proteins in the synaptic bouton complex across different tissues sampled by the Human Protein Atlas. This shows the complex is highly specific for cerebral cortex tissue. No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.

    Techniques Used: Protein-Protein interactions, RNA Expression, Expressing, Functional Assay, Transmission Assay



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    Human Protein Atlas human tissue expression patterns
    Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA <t>expression</t> profiles of proteins in the synaptic bouton complex across different tissues sampled by the <t>Human</t> Protein Atlas. This shows the complex is highly specific for cerebral cortex <t>tissue.</t> No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.
    Human Tissue Expression Patterns, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human tissue expression patterns/product/Human Protein Atlas
    Average 90 stars, based on 1 article reviews
    human tissue expression patterns - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    human tissue expression pattern  (Human Protein Atlas)
    90
    Human Protein Atlas human tissue expression pattern
    Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA <t>expression</t> profiles of proteins in the synaptic bouton complex across different tissues sampled by the <t>Human</t> Protein Atlas. This shows the complex is highly specific for cerebral cortex <t>tissue.</t> No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.
    Human Tissue Expression Pattern, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human tissue expression pattern/product/Human Protein Atlas
    Average 90 stars, based on 1 article reviews
    human tissue expression pattern - by Bioz Stars, 2026-02
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    Image Search Results


    Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA expression profiles of proteins in the synaptic bouton complex across different tissues sampled by the Human Protein Atlas. This shows the complex is highly specific for cerebral cortex tissue. No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.

    Journal: Molecular Systems Biology

    Article Title: Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

    doi: 10.15252/msb.20167490

    Figure Lengend Snippet: Presence/absence matrix of BioPlex AP‐MS experiments as rows and pulled down proteins as columns for four complexes identified in our complex map. The Exosome, eIF3 Complex, and 19S Proteasome all have multiple bait–bait interactions whereas the novel synaptic bouton complex does not have bait–bait interactions but does have substantial density in the non‐bait region of the matrix. This density is identified by the weighted matrix model and highlights the model's ability to discover protein complexes. RNA expression profiles of proteins in the synaptic bouton complex across different tissues sampled by the Human Protein Atlas. This shows the complex is highly specific for cerebral cortex tissue. No less than six replicates were used for each tissue type. Boxes indicate median (inner band), first quartile (bottom) and third (top) quartile. Whiskers indicate 1.5 interquartile range. Dots indicate outliers. Correlation coefficient distributions of Allen Brain Map tissue expression profiles between synaptic bouton complex proteins and random set of proteins. This shows coherence of expression among proteins in the complex suggesting a functional module. Significantly enriched Gene Ontology annotations for proteins in the synaptic bouton complex shows enrichment for neuron development and synaptic transmission.

    Article Snippet: First, we annotated proteins in hu.MAP with information about their human tissue expression patterns from the Human Protein Atlas (Uhlén et al , ).

    Techniques: Protein-Protein interactions, RNA Expression, Expressing, Functional Assay, Transmission Assay